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ACRP ACRP-CP Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Study Design and Conduct | 17% | - Study implementation
|
| Topic 2: Professionalism and Ethical Practice | 15% | - Professional standards
|
| Topic 3: Data Management and Informatics | 17% | - Data collection
|
| Topic 4: Ethical and Participant Safety Considerations | 19% | - Ethical principles
|
| Topic 5: Clinical Study Operations | 15% | - Site management
|
| Topic 6: Regulatory and Compliance Requirements | 17% | - International standards
|
ACRP Certified Professional Sample Questions:
A PI is reviewing the CRF for a recent subject visit and notices the participant's heart rate and temperature are not recorded. Which of the following study documentation practices was neglected?
- A. Contemporaneous
- B. Attributable
- C. Complete
- D. Original
Correct Answer: C 🗳️
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A clinical trial where participants will be randomized to receive a sequence of two medications has which design configuration?
- A. Factorial
- B. Parallel Group
- C. Crossover
- D. Group sequential
Correct Answer: C 🗳️
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A double-blind randomized Phase III trial seeks to recruit 500 subjects in 2 years. At the end of the first year,
150 subjects have been enrolled. Monitoring reports from the first year note 50% of subjects screened were screen failures due to exclusionary lab values. What action should the sponsor take?
- A. Evaluate the screen failures to determine if the protocol needs revision.
- B. Allocate additional monitoring resources to the trial.
- C. Re-train investigators on recruitment obligations.
- D. Reduce the target sample size based on feedback from the sites.
Correct Answer: A 🗳️
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Who determines the age of assent for pediatric studies?
- A. Parent
- B. IRB/IEC
- C. Sponsor
- D. PI
Correct Answer: B 🗳️
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An audit was recently completed and identified non-compliance that could potentially affect the reliability of study results. Who should perform a root cause analysis and implement appropriatecorrective and preventive actions?
- A. IRB/IEC
- B. Sponsor
- C. DSMB/IDMC
- D. PI
Correct Answer: D 🗳️
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